Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Encephalopathy
ADR ID BADD_A01462
ADR Hierarchy
17      Nervous system disorders
17.13      Encephalopathies
17.13.02      Encephalopathies NEC
17.13.02.001      Encephalopathy
Description A disorder characterized by a pathologic process involving the brain. [CTCAE] Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. [MeSH]
MedDRA Code 10014625
MeSH ID D001927
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Encephalopathy | Encephalopathy acute | Encephalopathy chronic | Encephalopathy NOS | Encephalopathy, unspecified | Influenza encephalopathy | Brain Diseases | Brain Disease | Brain Disorders | Brain Disorder | Intracranial CNS Disorders | Central Nervous System Intracranial Disorders | CNS Disorders, Intracranial | CNS Disorder, Intracranial | Intracranial CNS Disorder | Encephalon Diseases | Encephalon Disease | Intracranial Central Nervous System Disorders | Central Nervous System Disorders, Intracranial | Encephalopathies
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Dihydropyrimidine dehydrogenase [NADP(+)]Q12882T75890
Gamma-aminobutyric acid receptor subunit beta-1P15431Not Available
TransketolaseP29401T67754
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00560Cytarabine0.000533%
BADD_D00564Dabigatran etexilate--
BADD_D00571Dactinomycin0.001066%
BADD_D00574Dalfampridine--
BADD_D00580Dapsone0.002405%
BADD_D00581Daptomycin0.000745%
BADD_D00589Dasatinib--
BADD_D00594Deferasirox0.023325%
BADD_D00597Deferoxamine mesylate--
BADD_D00611Desflurane--
BADD_D00623Dexamethasone0.005493%
BADD_D00648Diazepam0.001067%
BADD_D00653Diclofenac0.000296%
BADD_D00668Digoxin0.000636%
BADD_D00680Dimethyl fumarate--
BADD_D00686Diphenhydramine0.001010%
BADD_D00695Disulfiram0.034620%
BADD_D00696Divalproex sodium--
BADD_D00699Docetaxel0.000533%
BADD_D00718Doxazosin--
BADD_D00723Doxorubicin0.002931%
BADD_D00734Duloxetine--
BADD_D00774Entecavir0.029964%
BADD_D00775Enzalutamide--
BADD_D00788Epoprostenol--
BADD_D00800Erlotinib--
BADD_D00802Ertapenem0.001916%
BADD_D00809Escitalopram--
BADD_D00812Eslicarbazepine acetate--
BADD_D00850Etodolac0.001484%
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